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Q: What is the ratio of V0/Vmax when [S] = 10Km?

The Michaelis-Menten equation V0 = Vmax[S]/(Km + [S]) simplifies to V0/Vmax = [S]/(Km + [S]). Substituting [S] = 10Km yields V0/Vmax = 10Km/(10Km + Km) = 10/11. Thus, the reaction proceeds at 10/11 of its maximum rate.

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